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Autoantibody testingtechniques and interpretation: The International Autoimmune Hepatitis Group (IAIHG) recommends indirect immunofluorescence assay (IFA) for detecting ANA, ASMA, LKM-1, LC-1, and p-ANCA

Recent studies have shown that autistic disorder is likely to involve multiple genes [79] although a common genetic change is not seen in all cases suggesting that it is likely to be a cluster of conditions, each with its own individual and yet overlapping pathology

Superoxide is so damaging to cells that mutations in the superoxide dismutase enzyme can lead to ALS, which is characterised by the loss of motoneurons in the spinal cord and brain stem, possibly involving the activation of caspase-12 and the apoptosis cascade via oxidative stress