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When initiating tirzepatide or increasing the dose, women taking oral contraceptives should use an additional non-hormonal method for 4 weeks due to potential decreased effectiveness of oral contraceptives
Letter of medical necessity
In addition, clinical muscle function studies involving older men and women have observed that participants in the placebo group show declines in muscle strength over the course of the study [40, 41], relative to baseline, similar to this current report
A: The initial dosage for semaglutide is usually 0.25 mg once a week
This disparity could exacerbate negative emotions, thereby further increasing the risk of depression [44]
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