Phase 2 trial data (Jastreboff et al., NEJM 2023) identified nausea, vomiting, diarrhoea, and constipation as the most common GI side effects
While its exact mechanism of action remains unclear, its effectiveness is believed to stem from its interaction with H receptors, leading to increased histamine synthesis and release, a key neurotransmitter involved in wakefulness
Targeting myocardial substrate metabolism in heart failure: potential for new therapies
contact a GP or trial coordinator promptly for widespread rash, blistering, or skin changes accompanied by systemic symptoms
5 Tesamorelin LiverTox (NIH/NIDDK, 2018)Clinical and research information, including formulation storage (Egrifta vs Egrifta SV) and reconstitution handling