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GLP-1 drug use has nearly quadrupled since 2024, according to Gallups National Health and Well-Being Index, which found that roughly 11% of U.S

Clinical guidelines consistently recommend 10% or more total body weight loss for meaningful OA symptom improvement

Treatment options include surgical resection, chemotherapy (often using drugs like doxorubicin and ifosfamide), radiation therapy, and newer targeted therapies, such as MEK inhibitors, which focus on specific genetic mutations in the tumor

When this method is used in conjunction with radiotherapy, it shows a significant effect in reversing radiation resistance and effectively inhibiting tumor growth (82)

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