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Interestingly, we observed branching networks of human CD31-positive cells within the transplanted organoid that entered and extended throughout the mouse kidney parenchyma (Fig
By comparison, PT-141 powder for injection should first be reconstituted and then administered subcutaneously while following standard safety procedures
Nonetheless, its systemic injection in mice has demonstrated significant adverse effects, including renal failure and hemolysis, presenting a hurdle for in vivo application
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