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2019Oct 10;20(20):5023

Co-inhibition of Glutaminolysis and one-carbon metabolism promotes ROS accumulation leading to enhancement of chemotherapeutic efficacy in anaplastic thyroid cancer

Within the gastrointestinal tract, gut bacteria facilitate the conversion of choline and carnitine into trimethylamine (TMA), which is further metabolized in the liver to produce TMAO (Wang et al., 2011)