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The usual dose for vitamin B12 injections is 1000 mcg (1 mg), given by injection

Administration routes include intramuscular and subcutaneous injections

The absorption of B12 is a complicated process but the two main components that are needed are the Hydrochloric acid in your stomach, which releases the B12 from food, and a protein called Intrinsic Factor which is produced in the lining of your stomach and which enables the absorption of B12 in the Ileum

weight loss clinics combines compounded semaglutide with methylcobalamin (the active form of B12) in a single weekly injection

For neurological involvement, hydroxocobalamin 1mg should be given on alternate days until no further improvement, before moving to maintenance