glp-1 news today september 29 2025 obesity drug A network meta-analysis backed weight-loss Who Gets the Shot? GLP-1

Will Kirby holds a degree in Biology from Emory University and earned his medical degree from Nova Southeastern University

Why does your body need B12

So I'm going to throw it over to Geoff to answer that question first and then we'll go from there

As aesthetic medicine continues to evolve beyond surface-level treatments, a new category of therapies is gaining attention: peptide therapy

The mutation of GLP-1 Phe 28 to Ala causes it to lose nearly all of its affinity (IC 50 : 0.27 nM357 nM), and Ile 29 mutation decreases the affinity notably (IC 50 : 0.27 nM25 nM), while Trp 31 , Leu 32 , and Val 33 mutations have little influence, showing that they may be merely subsidiary.25 The Val 23 and Ile 27 used in tirzepatide are likely to have little impact on either GLP-1 or GIP activity because they are the same kind of residue and no specific interaction in these sites has been detected