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Confocal images were obtained using Olympus FV1000 and Andor Dragonfly microscopes, and images were captured using Olympus Fluoview and Fusion, respectively, and compiled using ImageJ software

Study Design The Delphi methodology was selected as a widely recognised, systematic and robust process for eliciting expert consensus

And it delivers copper to enzymes called lysyl oxidase and lysyl hydroxylase, which are responsible for cross-linking collagen fibers into strong, stable structures

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