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GLP-1 RA functions by activating the GLP-1 receptor (GLP-1R), and GLP-1R is widely located throughout the brain.6,7 The ability of GLP-1 and its agonists to cross the bloodbrain barrier810 suggests its therapeutic potential for NDs

This increases the bodys basic metabolism, even when sleeping, leading to overall weight loss, specifically targeting fat

Researchers should interpret the cited literature within the experimental context of each individual study

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Safety, side effects, and who should pause before starting All GLP-1 receptor agonists and the GIP/GLP-1 dual agonist tirzepatide share a well-characterized side-effect profile: nausea, vomiting, diarrhea, constipation, abdominal pain, and headache are common