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(2023) demonstrated that moderate Drp1 upregulation in ALS Drosophila models restores physiological mitochondrial distribution within axons, enabling efficient mitochondrial trafficking to nerve terminals and thereby meeting axonal energy demands

If diarrhoea is accompanied by fever, blood in stools, severe abdominal pain, or dehydration, an infectious or inflammatory cause should be considered and medical attention sought promptly

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Potency and PK anchors: Lau 2015 (cAMP EC50 6.2 pmol/L), Boianelli 2024 (free fraction 0.36%), FDA 2021 (weight-change EC50 54.6 nmol/L)

It upregulates actin, a cell-building protein involved in cell migration and tissue repair