Lithium, Neurotransmitters, and Receptors Lithium generally influences neurotransmitter systems, balancing excitatory and inhibitory neurotransmitters, increasing GABA/glutamate ratios, and acetylcholine/catecholamine activity to stabilize mood [58] (Fig
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Notably, a dose-dependent increase in heart rate, peaking at 24 weeks, subsequently decreased [19]
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