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One of the central regulatory pathway in redox balance is the Kelch-like ECH-Associating protein 1 (Keap1)nuclear factor erythroid 2 related factor 2 (Nrf2)antioxidant response element (ARE) pathway, which upregulates biosynthesis of antioxidant proteins, including antioxidant enzymes such as heme oxygenase-1 (HO-1), glutathione S -transferase, NAD(P)H:quinone oxidoreductase 1 (NQO1), glutathione reductase (GR), Trx-R, CAT, and SOD, but also nonenzymatic antioxidant proteins, e.g., Trx or anti-apoptotic proteins from Bcl-2 family 64

doi:10.1016/S0009-9236(98)90177-1

Then he eats breakfast, which is a few pounds of vegetables like broccoli, cauliflower, garlic and ginger, he explains, all of which are chosen for their health-boosting benefits

Written informed consent to participate in this study was provided by the participants or their legal guardian/next of kin