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This 24-week clinical trial demonstrated that supplementation with Glutathione precursors (GlyNAC) in 8 generally healthy individuals boosts GSH levels and improves oxidative stress, mitochondrial function, inflammation, physical and cognitive function.

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In details, the transcriptional levels of HDAC1 and HDAC2 are decreased in the granule cells and the pyramidal cell layer of hippocampus in the acute stage of KA-induced epilepsy

doi.org/10.1016/j.molmed.2005.07.004 Crockford, D., et al