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Begin with your normal daily water intake (around 2.7 liters or 9 cups) and increase to 3 to 3.5 liters over the first week as you start the lowest tirzepatide dose

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However, because all studies included in our systematic review had small sample sizes, small-study effects might have influenced our findings

Glucagon-like Peptide-1 Receptor Agonists for Treatment of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis: An Updated Meta-Analysis of Randomized Controlled Trials