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Copper is involved in melanin synthesis (hair pigmentation) and is a cofactor for enzymes involved in keratin cross-linking
Its also worth noting that the term Rx (often seen on prescription drug labels or in pharmacies) is a common shorthand for prescription
For the LEfSe analysis, an alpha of 0.05 was set for the KruskalWallis tests among classes, and per-sample normalization was performed to bring the sum of the values to 1 M
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