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Briggs GG, Ambrose PJ, Nageotte MP, et al

Ferroptosis is negatively regulated by the enzymatic activity of GPX4, and increasing attention to possible ways of inhibiting this cell death modality are needed ( In order to test if our new activator could have a beneficial effect in the context of inhibiting cell death, we evaluated compound 102 for its ability to prevent erastin-induced ferroptosis

Although these compounds are often studied within similar experimental domains, their mechanistic profiles differ

L., Banerji M

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