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The drugs are made to keep GLP-1 levels elevated for longer periods so that they work to really control blood sugar and also reduce appetite longer, Kim said
PMCID: PMC3926176
As with many emerging peptides, robust human pharmacokinetic and dose-finding data are still developing
Intestinal OCT1 transport and GI intolerance with metformin Given the role of OCT1 in potentially altering local concentrations of metformin, our group (Dujic et al) proposed that a reduction in function of OCT1 might alter the risk of GI intolerance in patients treated with metformin [7]
This action helps move sugar from the blood into other body tissues
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