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(2016) "Brain-gut axis and pentadecapeptide BPC 157." Current Neuropharmacology, 14(8):857-865

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Methylation is a key process for metabolizing estrogen, catecholamines, histamine, heavy metals such as arsenic, pesticides, polycystic aromatic hydrocarbons from smoke and grilled foods, and phenols found in plastics, petroleum, etc

In addition, several molecules have been studied as an adjuvant therapy, including L-carnitine, CoQ 10 , vitamin E, vine tea polyphenol, cytoprotective agents (ursodeoxycholic acid), and insulin sensitizers (pioglitazone and metformin) (94)

N-acetylcysteine (NAC) protects the liver via diverse antioxidant and immunomodulatory actions