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Dysregulation of these pathways contributes jointly to the pathological states involved in PCOS, such as IR, HA, OS, and inflammation ( Figure 7 )

The body's response to GLP-1 activation follows a dose-response curve, meaning higher concentrations of the same receptor signal do not linearly improve outcomes

PMID 27755171 Iriarte, C., Awosika, O., Rengifo-Pardo, M., & Ehrlich, A

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First, FBFs are suggested to repress expression of MPK-1, a homolog of Mitogen-activated protein kinase (MAPK)/ERK, and mpk-1 mRNA contains two FBF binding elements in its 3UTR (Lee et al., 2007a)