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Briefly, the cells were cultured in Dulbecco's modified Eagle's medium (DMEM, Nacalai Tesque, Inc.) supplemented with 10% fetal bovine serum (Gibco

Astrocytes also play a role in the localized innate immune system and their disruption has detrimental autoimmune and neurological consequences 8,16,17

The ferroptosis inducing compounds RSL3 and ML162 are not direct inhibitors of GPX4 but of TXNRD1