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Unopened Wegovy pens must be stored in a refrigerator between 2C and 8C until first use Once removed from the fridge, Wegovy can be kept at room temperature below 30C for up to 28 days Never freeze Wegovy pens as this permanently destroys the active semaglutide compound Protect your pens from direct sunlight and extreme temperatures at all times Always check your medication for discolouration or particles before each injection Wegovy Storage Temperature Checker Use this tool to check if your Wegovy storage conditions are safe

No effect of sex was detected in the proteomic response to semaglutide treatment in either STEP 1 or STEP 2 (Supplementary Tables 4 and 5)

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Patients with a history of bipolar disorder, severe anxiety, or psychosis might experience worsening of symptoms

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