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This, in turn, raises circulating insulin-like growth factor-1 (IGF-1) levels

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Pillar 1: Activity (aerobic + resistance + daily movement) Physical activity improves insulin sensitivity through several mechanisms at once: increased glucose uptake (including non-insulin-mediated uptake), improved muscle insulin signalling, reduced intramuscular lipid burden (DAGs), improved hepatic insulin sensitivity, and improved appetite regulation via brain signalling

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BMA sets out GP advice on Mounjaro prescribing due to launch next week The BMA has set out advice for the time and costs for GPs in setting up locally commissioned services to provide tirzepatide (Mounjaro) weight loss injections on the NHS