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Vitamins B6, B12, and E also support glutathione production and function.

NETosis is an important neutrophil function that can promote liver metastasis of breast cancer and different pro-metastatic neutrophil populations are highly metabolically adaptable, which facilitates the formation of liver metastases (145)

Because the escalation phase occupied a large share of the study window and the trial ended at 46 weeks, the weight-loss curves had not clearly plateaued at every dose, meaning the ceiling of effect for survodutide in obesity remained an open question at Phase 2