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153155 Regulation Mechanism of TMAO in the Gut-Organ Axis: Crosstalk in Cell Death Cell death is usually divided into two types: accidental cell death and regulated cell death (RCD)
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The gut microbiota exerts significant regulatory effects on the brain-gut axis through immune, neuroendocrine, and direct neural mechanisms, influencing neurodevelopment, brain function, and behavior (7, 8)
SOS is the most typical histological change, and is characterized by impaired sinusoidal wall integrity, sinusoidal hyperemia and blockage, sinusoidal fibrosis, fibroid blockage in the lobular central vein and nodular hyperplasia or hemacelinosis (18)