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So it is a little pre-GLP-1s being in the mainstream culture

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When metformin alone is insufficient, NICE recommends considering the addition of one of several medication classes: SGLT2 inhibitors (such as dapagliflozin, empagliflozin, or canagliflozin) work by increasing glucose excretion through the kidneys

The Two Main Incretin Hormones[i] GLP-1 : Released by the L-cells of the small intestine, GLP-1 stimulates insulin secretion, inhibits glucagon release (a hormone that raises blood glucose), slows gastric emptying, and promotes satiety, helping to control appetite

GLP-1 receptor agonists like Wegovy , Ozempic , and Mounjaro work by: Slowing digestion to keep you feeling full longer Reducing appetite and calorie intake Enhancing insulin secretion and lowering blood sugar levels These effects support sustainable weight loss , improved metabolic health, and in many cases, diabetes remission