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Wiese C, Rolletschek A, Kania G, Blyszczuk P, Tarasov KV, Tarasova Y, Wersto RP, Boheler KR, Wobus AM

In the sections below, we delve into how disruptions in these MGBA pathways have been implicated in specific neurodegenerative diseases

While NSAIDs undermine healing by damaging the gut lining and impairing tissue repair, opioids affect pain through a completely different pathway by suppressing pain perception within the central nervous system rather than addressing inflammation or injury

Miura et al

2.3.5 Epigallocatechin gallate (EGCG) EGCG, the principal catechin of green tea ( Camellia sinensis ), attenuates PsO-like inflammation through inhibition of STAT3 phosphorylation, NF-B signaling, and Th17 differentiation [52] In keratinocyte and IMQ mouse models, EGCG reduces IL-17/IL-22 production, oxidative stress, and keratinocyte hyperproliferation