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At the molecular level, 3-OM and 4-OF lines demonstrated increased SA--gal signals and p16 expression, two widely used senescence biomarkers, in comparison to those in the young cells (1-YM & 2-YF) (Fig

There are some mushrooms such as Trametes versicolor , Schizophyllum commune , Flammulina velutipes , Ganoderma lucidum , Phellinus linteus, Lentinus edodes, Cordyceps sinensis, Inonotus obliquus , and Grifola frondosa that possesses inhibitory effects toward cancer as well their immuneceuticals actions, mainly via the elevation of the immune system of the host

Kim SH, Kim D, Lee J-M, Lee SK, Kang HJ, Yeo SG

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Cell signaling pathways offer potential targets, as they involve complex interactions that can be modulated to address multiple clinical symptoms