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Together, these findings reveal that prostate cancer cells are exquisitely sensitive to metabolic perturbations that affect the balance between glucose and the pentose phosphate pathway and implicate PFKFB4 as a potential therapeutic target (Ros et al 2012)
Additionally, dysfunctional Nrf2 cannot effectively regulate immune responses, leading to the excessive release of inflammatory factors, which worsens joint inflammation and damage
Glutamate acting on AMPA but not NMDA receptors modulates the migration of hippocampal interneurons
This review is distinct from prior analyses by focusing not only on ASTs molecular mechanisms but also on its delivery challenges, bioavailability, and translational relevance
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