There are post marketing reports of acute kidney injury and worsening of chronic renal failure
Cancer cell enrichment was measured using the following cell surface expression markers: fibroblast specific protein-1 (mouse 1:400, secondary goat anti-mouse IgG Alexa 488 1:2000), CD31 (mouse PE-conjugated, 1:200), CD14 (mouse PerCP Cy5.5, 1:200), B220 (mouse PE-Cy5, 1:200), and CD44 (human, APC conjugated), and the percentage of CD44 pos cancer cells was measured by flow cytometry (Supplemental Fig
Some peptide-based medications are FDA-approved for specific uses, while many compounded peptide preparations are not
Imaging was performed with a Zeiss Axio Observer.Z1 microscope with a Yokogawa spinning disk confocal head, Cascade IIL:512 camera, a quad-band notch dichroic mirror (405, 488, 568 and 647 nm) and 405-nm, 491-nm, 561-nm and 640-nm lasers (all 50 mW)
Recalculating doses after any protocol change ensures accuracy continues