glutathione liver enzymes Dysregulation of synthesis in disease Glutathione: Pharmacological aspects and implications

An acidic or basic constituent also contributes to specific interactions in solutions from the Lewis electron donor-acceptor point of view

Some clinical studies have found elevated lactate levels (395, 396) in ME/CFS patient blood, cerebrospinal fluid, and muscles, suggesting there is reduced oxidative phosphorylation and a switch to anaerobic glycolysis (392, 397399)

Given the growing body of literature on CHAC proteins, a comprehensive overview of all published work is beyond the scope of this review

Glutathione has no known interactions

Therefore, targeting cellular oxidative stress through antioxidants has been suggested as a potential therapeutic option against neurological disorders, particularly using natural plant extracts