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When released (e.g., with vesicle depletion by reserpine or amphetamine) [69,70,152] it can substitute disturbed dopamine (i.e., shortage (reserpine) [69] or excess (amphetamine) [70]) as competing successfully for sites at dopamine receptors (i.e., counteracting the adverse effects of both dopamine agonists [70,152,153] and dopamine antagonists [68,70,152])

Partially, and only for heart rate

In my opinion, you should only consider surgery after giving rehabilitation a fair chance (at least 3-6 months) because it comes with a long recovery time, potential complications, and a very high cost

doi: 10.1016/j.mam.2008.08.006 83 FossumC