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Description

IL-6 is instantaneously produced in response to infection and tissue damage, and contributes to the hosts defence against emergent stress by activating the acute phase and immune response (Tanaka et al

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Especially, IGFBP7 may compete with IGF to bind to the extracellular domain of IGF-IR and then suppress the activation of IGF-IR by IGF [26]

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PMID 21418662

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Translation from animal studies to human applications

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TMAO causes vascular dysfunction and hypertension, two important risk factors for ischemic stroke [77]

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