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After administration, Sermorelin is rapidly broken down by enzymes, with the peptide typically remaining in circulation for only a short time

doi: 10.1016/j.intimp.2009.09.020

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The theory described in the peptide literature is that a GHRH analog (signal one) and a ghrelin-receptor agonist (signal two) act in a complementary, even synergistic, way producing a larger GH pulse together than either pathway alone, because the pituitary carries co-receptors for both inputs

Eating antioxidant rich foods, maintaining good sleep habits, and reducing alcohol or pollution exposure can support better results from supplementation