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Selenium Rich Foods and Vitamin C Serve as Glutathione Cofactors Selenium, an essential trace mineral abundantly present in foods such as sardines, liver, and sunflower seeds, is crucial for the enzymatic processes that support the activity of glutathione and glutathione related enzymes

It has also been reported that obese women with high GPx activity have an altered cardiometabolic profile, evidenced by insulin resistance predominantly affecting the liver, altered carbohydrate and lipid metabolisms, and a larger wall thickness of blood vessels than those with lower GPx activity

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The cellular uptake of iron is primarily facilitated through the binding of transferrin-bound iron to transferrin receptors, which internalize the iron into cells (41)

Defects in mitochondrial dynamics disrupt the allocation of mtDNA throughout the network and subsequently lead to mitochondrial dysfunction and increased ROS