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"Copper uglies" as a visible, predictable phase experienced by a meaningful proportion of users is community anecdote built on that research, not itself demonstrated

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In rare instances, GLP-1 drugs can cause more serious side effects

Individuals with a history of medullary thyroid carcinoma (a rare neuroendocrine tumor known as MTC) or multiple endocrine neoplasia syndrome type 2 (a hereditary cancer known as MEN 2) should not take semaglutide due to an increased risk of thyroid C-cell tumors in rodents

Patients most commonly present with a mole on their face or a mole on the body as these are easy to see