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Kim YC, Shin MD, Hackett SF, Hsueh HT, Lima ESR, Date A, Han H, Kim BJ, Xiao A, Kim Y, Ogunnaike L, Anders NM, Hemingway A, He P, Jun AS, McDonnell PJ, Eberhart C, Pitha I, Zack DJ, Campochiaro PA, Hanes J, Ensign LM

Published studies used once-weekly injections and planned escalation

The evidence reviewed herein does not yet support formal treatment guidelines, given the predominance of low-level data and the absence of head-to-head trials in MC4R -deficient populations

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If we notice that you're regressing or not hitting the benchmarks needed to accomplish your goals, we adjust your plan