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10.18632/oncotarget.19900 116 LiangZ.ZhangT.ZhanT.ChengG.ZhangW.JiaH.et al (2021)

VEGF plays a key role in angiogenesis and vascular permeability, but its overexpression can damage endothelial function and epithelial mesenchymal transition (Zhang Y

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In this two-step reaction, sodium azide (NaN 3 ) and 3-amino-1H-1,2,4-triazole (3-AT) selectively inhibit the hydrogen peroxide scavenging reaction of catalase [16] [17] NaN 3 inhibits the reaction of heme iron [Porphyrin Fe(III)] in the above reaction Equation (1), and 3-AT is thought to inhibit the reaction of Compound I [Porphyrin Fe(IV) = O] in the above reaction Equation (2)

In a recent study, neuroleptic-naive patients showed lower prefrontal D1R availability compared to healthy control subjects revealed by PET, suggesting a reduction of prefrontal D1R density in the pathophysiology of schizophrenia [70]