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2003;41(4 Suppl 4):S13

Key safety points from published literature: No reported deaths attributed to sermorelin in clinical trials or post-marketing surveillance No organ toxicity identified with therapeutic dosing No significant cardiovascular events linked to sermorelin use No evidence of pituitary damage or desensitization with appropriate dosing protocols (Vittone et al., 1997, JCEM ) Serious adverse reactions would most likely occur with: Unsupervised use at excessively high doses Use in patients with contraindicated conditions (active cancer, pituitary tumors) Use of non-pharmaceutical-grade products from unregulated sources Long-Term Safety: Is Sermorelin Safe Over Time

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doi:10.1016/j.phymed.2010.01.007

Its ability to increase eumelanin content supports investigation into protective pigmentation responses