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The inhibitory effect of betulin on SREBP2 maturation in HEB cells is weaker than in U87 and T98G cells, showing a pattern similar to that of the combined treatment with metformin and simvastatin (Fig

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CYP2R1 expression was not seen in FL83B mouse hepatocytes) and 1--hydroxylase (CYP27B1), along with the increased expression of 24-hydroxylase (CYP24A1), was observed in GSH-deficient hepatocytes