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Moreover, the abundance of erythrocytes in circulation [23] raises an additional question concerning the possible immunogenic consequences of erythrocyte RCDs

20) and then evaluate their biological properties

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Elevations in MDH activity was found to correlate with morphological changes after dosing with thioacetamide, dimethylonitrosamine and diethanolamine [98]

Ideally, these products should be isotonic, but hypertonic solutions (up to 600 mOsm/kg) are sometimes used to reduce injection volume, although higher osmolality can increase pain