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For many patients, early changes may appear within weeks 2 to 4, especially when appetite suppression leads to reduced calorie intake

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It is possible that, in addition to factors such as reduced alcohol consumption, weight loss-related improvements in body image, or relief associated with better glycemic control in diabetes, there may also be direct neurobiological mechanisms involved, for example, through changes in the functioning of the brains reward system, says Research Director, Docent Markku Lhteenvuo from the University of Eastern Finland

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Patients assume refrigeration means colder is better and mistakenly put pens in the freezer