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Blunts the peptide's ability to activate growth hormone gene transcription, even though plasma tesamorelin levels follow the expected 2638 minute half-life curve

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Sanyal AJ, Kaplan LM, Frias JP, Brouwers B, Wu Q, Thomas MK, Harris C, Schloot NC, Du Y, Mather KJ, Haupt A, Hartman ML (2024) Triple hormone receptor agonist retatrutide for metabolic dysfunction-associated steatotic liver disease: a randomized phase 2a trial

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In lymphocytes, vitamin C increases cellular proliferation and antibody production, allowing more efficient opsonisation of pathogens for destruction