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Energize your weight loss program

Journal of the International Society of Sports Nutrition, 9 , 43

Understanding who benefits most prevents wasted money and disappointment

The early phase focuses on allowing your body to adjust while minimizing potential side effects as your system adapts to this gradual metabolic change

Key Points Metabolism has a key role in the physiological turnover of synovial joint tissues, including articular cartilage In osteoarthritis (OA), chondrocytes and cells in joint tissues other than cartilage undergo metabolic alterations and shift from a resting regulatory state to a highly metabolically active state Inflammatory mediators, metabolic intermediates and immune cells influence cellular responses in the pathophysiology of OA Key metabolic pathways and mediators might be targets of future therapies for OA Abstract Metabolism is important for cartilage and synovial joint function