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3.4.4.2 Prebiotics In a male rat model of PTSD-like symptoms induced via amygdala hyperactivation (a key pathophysiological mechanism of PTSD)3 weeks of treatment with the prebiotic GOS restored microbial homeostasis by enriching beneficial Bifidobacterium animalis and Limosilactobacillus reuteri , while eliminating harmful Enterococcus casseliflavus (Ruciski et al., 2025)

However, further retrospective case series have identified liver injury and hepatotoxicity in children following paracetamol intoxication, particularly following multiple sequential overdoses , and that the mortality in these cases can be high

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NAION occurs as the result of reduced blood flow to the optic nerve, which connects the eye to the brain, causing sudden, permanent blindness in one eye

To reduce potential gastrointestinal side-effects supplements were increased by 10 g/day every 2 weeks to reach the 30 g/day dose