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doi: 10.3390/antiox9090878

Hematin Therapy Acute porphyrias are a group of rare, inherited metabolic disorders marked by intermittent, potentially life-threatening attacks severe abdominal pain, neurological complications, and in some cases, cutaneous sensitivity

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Plantinga Y, Ghiadoni L, Magagna A, Giannarelli C, Franzoni F, Taddei S, Salvetti A

Symptoms of an allergic response include a new itching rash or hives, swelling (particularly around the eyes/lips), burning or stinging, and red spots or dry, flaky areas that emerge in strange places and intensify with each application