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It is a once-weekly investigational triple agonist designed to activate three metabolic receptor pathways at the same time: GLP-1, GIP, and glucagon
From there, researchers continued to push forward, eventually creating semaglutide
[DOI] [PMC free article] [PubMed] [Google Scholar] 44.Palta P., Samuel L.J., Miller E.R., Szanton S.L
This signalling not only promotes glucose uptake but modulates other functions involved in blood pressure regulation, such as NO-mediated vasodilation (99102), AII signalling (103,104) and antinatriuretic activity (105)
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