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The notice from the BMS suggests those using both oral HRT and GLP-1s switch to a higher dose or stronger form of progestin to preserve the protection the hormone provides against endometrial cancer

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While supply appears to have stabilized as of late, both tirzepatide (Zepbound and Mounjaro) and semaglutide (Ozempic and Wegovy) had been on the FDA shortage list in the past