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FGF-2, also known as basic FGF (bFGF), is the most characterized pro-angiogenic mediator in physiological conditions as well as during tumor progression [136, 137]
BPC-157 has demonstrated consistent healing effects in animal models, accelerating repair of tendons, ligaments, and muscles across various delivery methods
By transiently overexpressing LSH after USP5 knockdown, we found that USP5 promoted HCC cell proliferation by stabilizing LSH, and that upregulation of USP5 was associated with poor patient survival 139
Survival of Her2/neu mice was increased by treatment with CCXC872, a small molecule antagonist targeting CCR2
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