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The platforms most significant documented concern is the beyond-use date extension practice: patients have received medications with extended BUDs accompanied by company letters citing stability testing

Frozen tissues were thawn, carefully minced in lysis Buffer (10 mM Tris-Hcl, 146 mM NaCl, 21 mM MgCl 2 , 1 mM CaCl 2 , 0.1% CHAPs pH = 7.4) and grinded by using a tight douncer (Thermo Fisher Scientific, Waltham, MA, United States) on ice

Wang X, Zhang Z, Yan X, Qu Y, Lai Y, Li J

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